|
|
L-homoserine + NADP+ <=> L-aspartate_4-semialdehyde + NADPH + H+
|
1.1.1.3
homoserine dehydrogenase
|
–
|
BMK
|
|
BRENDA:
BR26051
KEGG:
R01775
MetaCyc:
HOMOSERDEHYDROG-RXN
SABIO-RK:
1868
|
|
|
|
L-homoserine + NAD+ <=> L-aspartate_4-semialdehyde + NADH + H+
|
1.1.1.3
homoserine dehydrogenase
|
–
|
K
|
|
BRENDA:
BR26051-a
KEGG:
R01773
MetaCyc:
HOMOSERDEHYDROG-RXN_WOP
|
|
|
|
S-adenosyl-L-methionine + H2O <=> S-methyl-5''-thioadenosine + L-homoserine + H+
|
3.3.1.2
S-adenosyl-L-methionine hydrolase (L-homoserine-forming)
|
–
|
|
|
BRENDA:
BR26097
KEGG:
R00175
MetaCyc:
ADENOSYLMETHIONINE-HYDROLASE-RXN
|
|
|
|
L-homoserine + acetyl-CoA <=> O-acetyl-L-homoserine + CoA
|
2.3.1.31
homoserine O-acetyltransferase
|
–
|
BMK
|
|
BRENDA:
BR44031
KEGG:
R01776
MetaCyc:
HOMOSERINE-O-ACETYLTRANSFERASE-RXN
SABIO-RK:
1869
|
|
|
|
L-homoserine + succinyl-CoA <=> O-succinyl-L-homoserine + CoA
|
2.3.1.46
homoserine O-succinyltransferase
|
–
|
BMK
|
|
BRENDA:
BR44047
KEGG:
R01777
MetaCyc:
HOMSUCTRAN-RXN
|
|
|
|
L-homoserine + ATP <=> H+ + O-phospho-L-homoserine + ADP
|
2.7.1.39
homoserine kinase
|
–
|
BMK
|
|
BRENDA:
BR47776
KEGG:
R01771
MetaCyc:
HOMOSERKIN-RXN
SABIO-RK:
1866
|
|
|
|
L-homoserine <=> 2-oxobutyrate + NH3
|
4.3.1.19
threonine ammonia-lyase
4.4.1.1
cystathionine gamma-lyase
4.4.1.11
methionine gamma-lyase
|
–
–
–
|
|
|
BRENDA:
BS141657;
BS391846
MetaCyc:
HOMOSERDEAM-RXN
|
|
|
|
L-cystathionine + H2O <=> L-cysteine + L-homoserine
|
4.4.1.1
cystathionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19007
MetaCyc:
CYSTATHIONASE-RXN
|
|
|
|
S-methyl-L-methionine + H2O <=> Dimethylsulfide + L-homoserine + H+
|
3.3.1.2
S-adenosyl-L-methionine hydrolase (L-homoserine-forming)
|
–
|
|
|
BRENDA:
BS364744
MetaCyc:
RXN-19156
|
|
|
|
L-homoserine <=> D-homoserine
|
5.1.1
5.1.1.10
amino-acid racemase
|
–
–
|
|
|
BRENDA:
BS445403
MetaCyc:
RXN0-7285
|
|
|
|
H+ + L-homoserine <=> H+ + L-homoserine
|
5.1.1.10
amino-acid racemase
|
–
|
|
|
BRENDA:
BS849
MetaCyc:
TRANS-RXN-242
|
|
|
|
L-homoserine <=> H+ + 2-aminobut-2-enoate + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-14049
|
|
|
|
(5E,7E,9E,11E,13Z)-5,9,11,13-tetramethylpentadeca-5,7,9,11,13-pentaene-2,4-dioyl-[acp] + L-homoserine + ATP + NADPH <=> prefusarin + [acyl-carrier_protein] + AMP + diphosphate + NADP+ + H2O
|
6.3.2
|
–
|
M
|
|
MetaCyc:
RXN-16739
|
|
|
|
L-homoserine + NH3 + acceptor <=> L-canaline + reduced_acceptor + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-25
|
|
|
|
H+ + L-canaline + NADPH <=> L-homoserine + NH3 + NADP+
|
1.6.6
|
–
|
M
|
|
MetaCyc:
RXN-35
|
|
|
|
L-homoserine + H2O + O2 <=> 4-Hydroxy-2-oxobutanoate + NH3 + H2O2
|
1.4.3.2
L-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS414769
|
|
|
|
butyryl-CoA + L-homoserine <=> CoA + O-butyryl-L-homoserine
|
2.3.1.31
homoserine O-acetyltransferase
|
–
|
|
|
BRENDA:
BS320793
|
|
|
|
L-homoserine + Sulfide <=> L-homocysteine + H2O
|
2.5.1.49
O-acetylhomoserine aminocarboxypropyltransferase
|
–
|
|
|
BRENDA:
BS380001
|
|
|
|
D-cysteine + L-homoserine <=> D-allocystathionine
|
4.4.1.1
cystathionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19008
|
|
|
|
N-(3-oxododecanoyl)-L-homoserine_lactone + H2O <=> L-homoserine + 3-Oxododecanoate
|
3.5.1.97
acyl-homoserine-lactone acylase
|
–
|
|
|
BRENDA:
BS380668
|
|
|
|
3-hydroxybutyryl-CoA + L-homoserine <=> CoA + beta-hydroxybutyryl-L-homoserine
|
2.3.1.31
homoserine O-acetyltransferase
|
–
|
|
|
BRENDA:
BS388218
|
|
|
|
2-oxosuccinamic_acid + L-homoserine <=> L-asparagine + 4-Hydroxy-2-oxobutanoate
|
2.6.1.14
asparagine---oxo-acid transaminase
|
–
|
|
|
BRENDA:
BS354198
|
|
|
|
L-homoserine + 3-Mercaptopropionate <=> S-carboxyethyl-L-homocysteine
|
4.4.1.1
cystathionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19021
|
|
|
|
propionyl-CoA + L-homoserine <=> CoA + O-propionyl-L-homoserine
|
2.3.1.31
homoserine O-acetyltransferase
|
–
|
|
|
BRENDA:
BS320792
|
|
|
|
crotonyl-CoA + L-homoserine <=> CoA + O-crotonyl-L-homoserine
|
2.3.1.31
homoserine O-acetyltransferase
|
–
|
|
|
BRENDA:
BS320795
|
|
|
|
L-aspartate_4-semialdehyde + L-homoserine <=> L-2,4-diaminobutanoate + 4-Hydroxy-2-oxobutanoate
|
2.6.1.76
diaminobutyrate---2-oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS423728
|
|
|
|
L-hSer-7-amido-4-carbamoylmethylcoumarin + H2O <=> L-homoserine + 7-amino-4-carbamoylmethylcoumarin
|
3.4.11.2
membrane alanyl aminopeptidase
|
–
|
|
|
BRENDA:
BS432027
|
|
|
|
glutaryl-CoA + L-homoserine <=> CoA + O-glutaryl-L-homoserine
|
2.3.1.31
homoserine O-acetyltransferase
2.3.1.46
homoserine O-succinyltransferase
|
–
–
|
|
|
BRENDA:
BS320797
|
|
|
|
isobutyryl-CoA + L-homoserine <=> CoA + O-isobutyryl-L-homoserine
|
2.3.1.31
homoserine O-acetyltransferase
|
–
|
|
|
BRENDA:
BS388943
|
|
|
|
N-octanoyl-L-homoserine_lactone + H2O <=> L-homoserine + Octanoate
|
3.5.1.97
acyl-homoserine-lactone acylase
|
–
|
|
|
BRENDA:
BS382379
|
|
|
|
N-dodecanoyl-L-homoserine_lactone + H2O <=> L-homoserine + laurate
|
3.5.1.97
acyl-homoserine-lactone acylase
|
–
|
|
|
BRENDA:
BS380675
|
|
|
|
L-homoserine + 2-mercaptopropionic_acid <=> S-methylcarboxymethyl-L-homocysteine
|
4.4.1.1
cystathionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19022
|
|
|
|
L-homoserine_lactone + H2O <=> L-homoserine
|
3.1.1.81
quorum-quenching N-acyl-homoserine lactonase
|
–
|
|
|
BRENDA:
BS417155
|
|
|
|
N-(3-oxodecanoyl)-L-homoserine_lactone + H2O <=> L-homoserine + 3-oxodecanoate
|
3.5.1.97
acyl-homoserine-lactone acylase
|
–
|
|
|
BRENDA:
BS382338
|
|
|
|
L-homoserine + H2O + NAD+ <=> 4-Hydroxy-2-oxobutanoate + NH3 + NADH
|
1.4.1.1
alanine dehydrogenase
1.4.1.4
glutamate dehydrogenase (NADP+)
|
–
–
|
|
|
BRENDA:
BS441516
|
|
|
|
N-tetradecanoyl-L-homoserine_lactone + H2O <=> L-homoserine + myristic_acid
|
3.5.1.97
acyl-homoserine-lactone acylase
|
–
|
|
|
BRENDA:
BS380681
|
|
|
|
N-heptanoyl-L-homoserine_lactone + H2O <=> L-homoserine + Heptanoate
|
3.5.1.97
acyl-homoserine-lactone acylase
|
–
|
|
|
BRENDA:
BS382372
|
|
|
|
L-homoserine + 2-mercaptoethanol <=> S-hydroxyethyl-L-homocysteine
|
4.4.1.1
cystathionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19024
|
|
|
|
DL-aspartate-4-semialdehyde + NADPH + H+ <=> L-homoserine + NADP+
|
1.1.1.3
homoserine dehydrogenase
|
–
|
|
|
BRENDA:
BS451031
|
|
|
|
L-homoserine + thioglycerol <=> S-(2,3-dihydroxypropyl)-L-homocysteine
|
4.4.1.1
cystathionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19025
|
|
|
|
L-homoserine + 4-sulfanylbutanoic_acid <=> S-carboxy-n-propyl-L-homocysteine
|
4.4.1.1
cystathionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19023
|
|
|
|
L-homoserine + thioglycolic_acid <=> S-carboxymethyl-L-homocysteine
|
4.4.1.1
cystathionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19028
|
|
|
|
malonyl-CoA + L-homoserine <=> CoA + psychosine_sulfate
|
2.3.1.31
homoserine O-acetyltransferase
|
–
|
|
|
BRENDA:
BS389133
|
|
|
|
ATP + UDP-MurNAc-L-Ala-D-Glu + L-homoserine <=> ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-homoserine
|
6.3.2.13
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---2,6-diaminopimelate ligase
|
–
|
|
|
BRENDA:
BS443201
|
|
|
|
ATP + L-glutamate + L-homoserine <=> ADP + phosphate + gamma-L-Glu-L-homoserine
|
6.3.2.2
glutamate---cysteine ligase
|
–
|
|
|
BRENDA:
BS515
|
|
|
|
N-C11-(S)-homoserine_lactone + H2O <=> L-homoserine + Undecanoate
|
3.5.1.97
acyl-homoserine-lactone acylase
|
–
|
|
|
BRENDA:
BS380673
|
|
|
|
L-homoserine + L-homocysteine <=> L-homolanthionine
|
4.4.1.1
cystathionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19026
|
|
|
|
L-homoserine + D-homocysteine <=> L-homolanthionine
|
4.4.1.1
cystathionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19027
|
|
|
|
L-homoserine + glyoxylate <=> 4-Hydroxy-2-oxobutanoate + glycine
|
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.73
methionine---glyoxylate transaminase
|
–
–
|
|
|
BRENDA:
BS353995
|
|
|
|
2-Oxoglutaramate + L-homoserine <=> L-glutamine + 4-Hydroxy-2-oxobutanoate
|
2.6.1.15
glutamine---pyruvate transaminase
|
–
|
|
|
BRENDA:
BS356354
|
|
|
|
phenylpyruvate + L-homoserine <=> L-phenylalanine + 4-Hydroxy-2-oxobutanoate
|
2.6.1.14
asparagine---oxo-acid transaminase
|
–
|
|
|
BRENDA:
BS354206
|
|